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Multiple Sclerosis: Is THC better than CBD for pain control?

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CBD has many benefits for MS, but pain control may be better with combining 11 hydroxy THC and Delta 9 THC. Of course, some CBD should be added too. B-Myrcene, D-Limonene, and Phytol may also be some of the best terpenes for MS!

For medication interactions with Cannabis: https://wholeplantlife.com/cbd-and-thc.html

For medication interactions with d-limonene: https://wholeplantlife.com/d-limonene.html

Sources for the video:

Giacoppo, Sabrina & Mandolino, Giuseppe & Galuppo, Maria & Bramanti, Placido & Mazzon, Emanuela. (2014). Cannabinoids: New Promising Agents in the Treatment of Neurological Diseases. Molecules (Basel, Switzerland). 19. 18781-18816. 10.3390/molecules191118781.

Devinsky, O., Whalley, B. J., & Di Marzo, V. (2015). Cannabinoids in the Treatment of Neurological Disorders. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 12(4), 689–691. doi:10.1007/s13311-015-0388-0

Russo E. B. (2011). Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. British journal of pharmacology, 163(7), 1344–1364. doi:10.1111/j.1476-5381.2011.01238.x

Lorenzetti BB, Souza GE, Sarti SJ, Santos Filho D, Ferreira SH. Myrcene mimics the peripheral analgesic activity of lemongrass tea. J Ethnopharmacol. 1991;34:43–48

Rao VS, Menezes AM, Viana GS. Effect of myrcene on nociception in mice. J Pharm Pharmacol. 1990;42:877–878.

Sabrina Giacoppo, Giuseppe Mandolino, Galuppo Maria, Emanuela Mazzon, Placido Bramanti. Cannabinoids: New Promising Agents in the Treatment of Neurological Diseases. Molecules 2014, 19(11), 18781-18816; https://doi.org/10.3390/molecules 191118781.

Izzo, Angelo A. Et al. Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb. Trends in pharmacological sciences. Volume 30, Issue 10, October 2009, Pages 515-527

Do Vale TG1, Furtado EC, Santos JG Jr, Viana GS. Central effects of citral, myrcene and limonene, constituents of essential oil chemotypes from Lippia alba (Mill.) n.e. Brown. Phytomedicine. 2002 Dec;9(8):709-14.

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