Understanding cannabis and the Endocannabinoid system Part 1
Cannabis has a lot of medical and other uses. Feel free to do your own research on the subject. My email is email@example.com if you have questions about what you want to ask in private and not on YouTube. I have experience with both CBD and THC. I have my medical card and I am informed on the subject. Do not email me for the sale of anything because I don’t have anything to sell. I can give you recommendations to buy Hemp CBD oil online. My daughter uses Hemp for her epilepsy so I have knowledge of the benefits for that also.
I hope everyone found this informative and learned something new today. Have a great day and stay informed not influenced.
For many suffering from chronic illness, cannabis is a godsend. From those dealing with the wrath of inflamed digestive systems to the ones combating global musculoskeletal pain, and the millions who report that the agony in their heads is just the beginning of their symptoms—cannabis can help these fighters with their load of physical woes.
But why? To explain, we need to back up a bit. You probably know that cannabinoids (like the popular CBD and THC) interact with the body’s endocannabinoid system (ECS) and that our bodies produce natural endocannabinoids that work with the ECS receptors to maintain health in all the other bodily systems. But do you know what happens when we don’t produce enough of these endocannabinoids?
Endocannabinoid deficiency could be the cause behind irritable bowel syndrome, fibromyalgia, migraine, and other treatment-resistant syndromes. The ECS is present in every major bodily system, which is how its dysfunction can theoretically cause such a variety of conditions—and how cannabis manages to treat them.
These conditions, along with others that fall into this realm, are generally thought to be incurable and chronic, usually lasting for the rest of the sufferer’s life. I spoke with Dr. Russo about this matter, and he offered hope for chronic illness fighters, saying that since these conditions are generally acquired (rather than congenital, from birth), it seems to suggest an ECS disturbance is behind the illness. So hopefully it can be reversed in some fashion.
What is clinical endocannabinoid deficiency?
The theory of Clinical Endocannabinoid Deficiency (CED) explains that these health conditions are due to a deficiency in endocannabinoid levels, akin to the way neurotransmitter deficiencies are behind other illnesses—like serotonin deficiency in depression. In other words, the theory posits that the cause of these syndromes is an insufficient amount of endocannabinoids functioning in the ECS.
The study primarily focuses on IBS, migraine, and fibromyalgia—all of which involve increased pain sensations in the affected areas—but disorders that may fall under the CED rubric include PTSD, glaucoma, cystic fibrosis, types of neuropathy, phantom limb pain, neonatal failure to thrive, infantile colic, menstrual pain, repetitive miscarriages, hyperemesis gravidarum, bipolar disease, and many others. Many of these diseases are little understood and remain treatment-resistant.
All humans possess an underlying endocannabinoid tone that reflects levels of anandamide (AEA) and 2-arachidonoylglycerol (2-AG), the centrally acting endocannabinoids, their synthesis, catabolism, and the relative density of cannabinoid receptors in the brain. If endocannabinoid function were decreased, it follows that a lowered pain threshold would be operative, along with derangements of digestion, mood, and sleep among the almost universal physiological systems subserved by the endocannabinoid system (ECS).5 The CED theory also posits that such deficiencies could arise due to genetic or congenital reasons or be acquired due to intercurrent injury or disease that consequently produces characteristic pathophysiological syndromes with particular symptomatology.